Clinical Interests: Optimizing care for the critically ill newborn with a focus on discovering and implementing neuroprotective approaches to care.
Scholarly focus: Dr. Juul's research mission is to improve the neurodevelopmental outcomes of high‐risk neonates. As such, she has focused on developing preclinical models of neonatal brain injury, testing neuroprotective interventions, developing biomarkers of neonatal brain injury, and discerning and maintaining iron sufficiency in the preterm infant. Animal models used or developed in her lab include the Vannucci model of hypoxia ischemia, middle carotid artery occlusion as a model of stroke, novel models of neonatal stress in rodents, a ferret model of preterm encephalopathy, and a nonhuman primate model of perinatal asphyxia. Dr. Juul has been fortunate to translate her bench research on erythropoietin (Epo) neuroprotection to the bedside and was principal investigator of the NIH funded multicenter phase III Preterm Epo Neuroprotection Trial (PENUT; NCT01378273), and is multi‐principal investigator of a multicenter phase III of High‐Dose Erythropoietin for Asphyxia and Encephalopathy Trial (HEAL; NCT02811263). Dr. Juul is also an adjunct faculty for the UW graduate program in neuroscience.
2016‐2022 High‐dose Erythropoietin for Asphyxia and Encephalopathy (HEAL) CCC. 1U01NS092764‐ 01A1, NINDS. Sandra Juul, MD, PhD and Yvonne Wu MD, MS, Multi‐PIs. Total Award:
2021‐2026 Repurposing azithromycin for premature brain injury. NICHD R01 HD101422‐02. Role: Co‐ investigator. Total award: $2,087,401.
2018‐2023 HEAL‐EEG – Neurophysiologic measures of Epo treatment for hypoxic‐ischemic encephalopathy (HIE), NINDS. Role: Site PI University Washington School of Medicine, Total Award: $55,716
2019‐2021 Stem cells in addition to hypothermia for neuroprotection in perinatal hypoxic‐ischemic brain injury, Thrasher Grant Research Foundation. Role: Co‐PI, Total Award: $26,750
Administration/Education Roles: Dr. Juul became Division Head Jan 2015 and has actively recruited and hired new research and clinical faculty. Nationally, she has been the Chair of the neonatal subboard of the American Board of Pediatrics (yes, writing exam questions!), a member of the Committee of the Fetus and Newborn and liaison to the AAP Executive Committee and is past Chair of the Developmental Brain Disorders NIH study section, and co‐editor of Avery’s Diseases of the Newborn, 10th edition. She is a sought‐after speaker at National and International meetings. Locally, Dr. Juul participates in the research education of undergraduate students, residents and fellows in her lab, as well as the clinical education of pediatric residents and neonatology fellows. She is also a member of the promotions committee, founding member of the QI and Research Committee of the Newborn Brain Society, and Associate Director of the CHDD Strategic Planning Committee, Coordinator, Central Nervous System Injury Collaborative Research.